Basic Information
Chemical formula: Pt(C₆H₁₄N₂)I₂
Molecular weight: ~554.1 g/mol (based on Pt 195.08, C 12.01, H 1.01, N 14.01, I 126.90)
CAS number: Not directly found for this specific compound; the related chiral isomer (e.g., trans-L-or (SP-4-2)-) has CAS 66845327 – this compound is one of its optically pure forms.
Structure & Properties
Crystal system: Monoclinic, space group C2
Unit cell parameters: a = 14.048(4) Å, b = 7.588(3) Å, c = 11.502(4) Å, β = 98.446(5)°, V = 1212.80 ų
Intermolecular forces: Stabilised by N–H···I and C–H···I hydrogen bonds
Purity: Can be obtained in >99% purity by HPLC or similar methods
Main Uses
Key intermediate for oxaliplatin synthesis:
Prepare this diiodo complex from a chloroplatinate precursor using KI.
React with silver oxalate to replace the two iodides with oxalate, yielding oxaliplatin.
Anticancer research: Also studied as a precursor for novel platinumbased anticancer agents.
Synthesis
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