Replacement therapy in adults , and children and adolescents ( 0-18 years ) in : Primary immunodeficiency syndromes with impaired antibody production ( see section 4.4 ) Hypogammaglobulinaemia and recurrent bacterial infections in patients with chronic lymphocyticleukaemia , in whom prophy lactic antibiotics have fail. Hypogammaglobulinaemia and recurrent bacterial infections in plateau phase multiple myelomapatients who have failed to respond to pneumococcal immunisation. Hypogammaglobulinaemia in patients after allogeneic haematopoietic stem cell transplantation( HSCT )  Congenital AIDS with recurrent bacterial infections

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